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Retatrutide
Next-Gen Therapy
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Tirzepatide
Mounjaro® / Zepbound®
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Semaglutide
Ozempic® / Wegovy®
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| How it works | Targets appetite and metabolism for maximal fat loss potential. | Targets appetite plus metabolic signals for stronger results. | Reduces appetite and helps you feel full sooner. |
| Typical weight loss | 20–24% body weight* | 15–22% body weight | 10–15% body weight |
| Best for | Significant goals and patients needing the strongest support.* | Greater weight loss goals or plateau after semaglutide. | First-time GLP-1 users and moderate goals. |
| FDA status | Currently in Phase 4 clinical trials* | Approved | Approved |